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ea0063p284 | Pituitary and Neuroendocrinology 1 | ECE2019

The assessment of octreotide suppression test, ihc- and mr-structure, mr-signal of gh-producing pituitary adenoma for determining the prognosis of disease and management.

Pronin Vyacheslav , Zherebchikova Kristina , Malysheva Alena , Kozhevnikov Alexander , Kalinin Pavel , Astafina Lyudmila , Rotin Daniil , Vorontsov Alexander , Ambrosimov Alexander , Grigoriev Andrei , Shishkina Lyudmila , Pronin Eugeny , Azizyan Vilen , Godkov Ivan , Belysheva Elena , Demidova Tatiana , Poteshkin Yury

Introduction: A growth hormone-secreting pituitary adenoma (GH-PA) increases the risk of complications and death. Its management is determined by MRI data and decrease of insulin-like growth factor-1 (IGF-1) during the octreotide suppression test (OST). Currently, there is evidence that MRI-T2-hypointensive somatotropinoma and high expression of somatostatin receptors type 2 (SSTR2) according to immunohistochemical analysis (IHC) predict high efficacy of somatostatin ana...

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The assessment of octreotide suppression test, ihc- and mr-structure, mr-signal of gh-producing pituitary adenoma for determining the prognosis of disease and management.

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